Selected Publications
Neurodegeneration
- Neuraceq – Beta Amyloid Imaging
- Bullich et al. (2021) Early detection of amyloid load using 18F-florbetaben PET. Alzheimers Res Ther. 2021 Mar 27;13(1):67. doi: 10.1186/s13195-021-00807-6. Click here to access the pdf
- de Wilde et al. (2018) Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort: The ABIDE Project. JAMA Neurol. 2018 Jun 11. doi: 10.1001/jamaneurol.2018.1346. Click here to access the pdf
- Ceccaldi et al. (2018) Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study. Alzheimers & Dementia, Mar;14(3):293-305. doi: 10.1016/j.jalz.2017.09.009. Click here to access the pdf
- Sabbagh MN et al. (2017) Histopathology and Florbetaben PET in Patients Incorrectly Diagnosed with Alzheimer’s Disease. J Alzheimers Dis. 2017;56(2):441-446. doi: 10.3233/JAD-160821. https://pubmed.ncbi.nlm.nih.gov/27983552/
- Seibyl et al. (2016) Impact of Training Method on the Robustness of the Visual Assessment of 18F-Florbetaben PET Scans: Results from a Phase-3 Study. J Nucl Med. 2016 Jun;57(6):900-6. Click here to access the pdf
- Sabri et al. (2015) Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer’s disease: phase 3 study. Alzheimers Dement. 2015 Aug;11(8):964-74. Click here to access the pdf
- 18F-PI-2620 – Tau Imaging
- “Bullich et al. Evaluation of tau deposition using 18 F-PI-2620 PET in MCI and early AD subjects-a MissionAD tau sub-study“ Alzheimers Res Ther. 2022 Jul 27;14(1):105. doi: 10.1186/s13195-022-01048-x. Click here to acced the pdf
- Rullmann M et al. (2022) Multicenter 18F-PI-2620 PET for In Vivo Braak Staging of Tau Pathology in Alzheimer’s Disease. Biomolecules. 2022 Mar 16;12(3):458. doi: 10.3390/biom12030458. Click here to access the pdf
- Song et al. (2021) Feasibility of short imaging protocols for [18F]PI-2620 tau-PET in progressive supranuclear palsy. Eur J Nucl Med Mol Imaging. 2021 May 22. doi: 10.1007/s00259-021-05391-3. Click here to access the pdf
- Palleis et al. (2021) Cortical [18 F]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes. Mov Disord. 2021 May 5. doi: 10.1002/mds.28624. https://pubmed.ncbi.nlm.nih.gov/33951244/
- Brendel et al. (2020) Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy. JAMA Neurol. Published online July 07, 2020. Click here to access the pdf
- Mormino et al. (2020) Tau PET imaging with 18F-PI-2620 in aging and neurodegenerative diseases. Eur J Nucl Med Mol Imaging. 2020 Jun 23 Online first Click here to access the pdf
- Beyer et al. (2020) Early-phase 18F-PI-2620 tau-PET imaging as a surrogate marker of neuronal injury” Eur J Nucl Med Mol Imaging. 2020 Apr 21 Online first Click here to access the pdf
- Mueller et al. (2020) Tau PET imaging with 18F-PI-2620 in patients with Alzheimer’s disease and healthy controls: a first-in-human study. J Nucl Med. 2020 Jun;61(6):911-919. Click here to access the pdf
- 18F-DED – MAO-B Imaging
Nag et al. (2016) In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl. J Nucl Med. 2016 Feb;57(2):315-20. doi: 10.2967/jnumed.115.161083. Click here to access the pdf
Cardiovascular
- Florbetaben – Cardiac Amyloid Imaging
- Santarelli MF et al. (2021) Cardiac amyloidosis characterization by kinetic model fitting on [18F]florbetaben PET images. J Nucl Cardiol. 2021 Apr 16. doi: 10.1007/s12350-021-02608-8. https://pubmed.ncbi.nlm.nih.gov/33864226/
- Santarelli MF et al. (2021). Deep-learning-based cardiac amyloidosis classification from early acquired pet images. Int J Cardiovasc Imaging. 2021 Jul;37(7):2327-2335. doi: 10.1007/s10554-021-02190-7. https://pubmed.ncbi.nlm.nih.gov/33591476/
- Genovesi D et al. (2021) [18F]-Florbetaben PET/CT for Differential Diagnosis Among Cardiac Immunoglobulin Light Chain, Transthyretin Amyloidosis, and Mimicking Conditions. JACC Cardiovasc Imaging. 2021 Jan;14(1):246-255. doi: 10.1016/j.jcmg.2020.05.031. Click here to access the pdf
- Kircher M et al. (2019). Detection of cardiac amyloidosis with 18F-Florbetaben-PET/CT in comparison to echocardiography, cardiac MRI and DPD-scintigraphy. Eur J Nucl Med Mol Imaging. 2019 Jul;46(7):1407-1416. doi: 10.1007/s00259-019-04290-y. https://pubmed.ncbi.nlm.nih.gov/30798427/
- Law WP et al. (2016) Cardiac Amyloid Imaging with 18F-Florbetaben PET: A Pilot Study. J Nucl Med. 2016 Nov;57(11):1733-1739. doi: 10.2967/jnumed.115.169870. Click here to access the pdf
- 18F-GP1 – Thrombus Imaging
- Bing R et al. (2021) 18F-GP1 Positron Emission Tomography and Bioprosthetic Aortic Valve Thrombus. JACC Cardiovasc Imaging. 2022 Jan 11:S1936-878X(21)00845-7. doi: 10.1016/j.jcmg.2021.11.015. https://pubmed.ncbi.nlm.nih.gov/35033495/
- Tzolos E et al. (2021). Categorising myocardial infarction with advanced cardiovascular imaging. 2021 Aug 7;398(10299):e9. doi: 10.1016/S0140-6736(21)01329-5. https://pubmed.ncbi.nlm.nih.gov/34364527/
- Hugenberg V et al. (2021) GMP-Compliant Radiosynthesis of [18F]GP1, a Novel PET Tracer for the Detection of Thrombi. Pharmaceuticals 2021, 14(8), 739 Click here to access the pdf
- Lee N et al. (2019) Radiation dosimetry of [18F]GP1 for imaging activated glycoprotein IIb/IIIa receptors with positron emission tomography in patients with acute thromboembolism. Nucl Med Biol. May-Jun 2019;72-73:45-48. https://pubmed.ncbi.nlm.nih.gov/31330411/
- Chae SY et al. (2019) A phase 1, first-in-human study of 18F-GP1 positron emission tomography for imaging acute arterial thrombosis. EJNMMI Res. 2019 Jan 7;9(1):3 https://www.ncbi.nlm.nih.gov/pubmed/30617563
- Kim C. et al. (2018) Glycoprotein IIb/IIIa receptor imaging with 18F-GP1 positron emission tomography for acute venous thromboembolism: an open-label, non-randomized, first-in-human phase 1 study. J Nucl Med. 2019 Feb;60(2):244-249. https://www.ncbi.nlm.nih.gov/pubmed/29959214
- Lohrke J et al. (2017) 18F-GP1, a Novel PET Tracer Designed for High-Sensitivity, Low-Background Detection of Thrombi. J Nucl Med. 2017 Jul;58(7):1094-1099. Click here to access the pdf